More blood clot complications occurred in the migraine with aura group than in the migraine without aura group. For this reason, migraine with aura needs to be discussed with your doctor as a risk factor for blood clots. This is especially important for women using third generation contraceptives. (Yasmin, Ocella, and Yaz are examples of third generation combined oral contraceptives.)
This isn't the first study to link blood clots and migraine. Ferrara et al. (2012) found a relationship between migraine and elevated levels of Factor VIII and Factor IX. They also found that individuals with migraine were more likely to have either MTHFR or Factor V Leiden. In 2011, Kutal et al had almost identical results in a similar study. It seems safe to assume that there is a connection between migraine and thrombophilia.
Boyles (2008) points out, that we do not know for sure if thrombophilia is the link between migraines and blood clots. There could be another factor involved.
No matter what the link is between migraine and blood clots, patients need to make sure that doctors are aware of the blood clot risks associated with migraine, especially in those patients who have multiple blood clot risk factors.